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Should you run into the following problem:

gpg: lock not made: link() failed: Operation not supported gpg: can't lock

you have to add the following line to your gpg.conf which is usually located at ~/.gnupg


This disables locking entirely.

In case this doesn't solve your problem, please open System Preferences > GPGPreferences / GPG Suite > Send Report.

Please open Terminal and copy the output of the following two commands into your report:

cat ~/.gnupg/gpg.conf
cat ~/.gnupg/gpg-agent.conf